Bariatric surgery leads to reduced drug use over 15 years | Health


Friday, May 26, 2023 (HealthDay News) — Patients undergoing bariatric surgery have higher long-term use of lipid-lowering, cardiovascular and antidiabetic drugs than non-surgical obese patients less, according to a study published online May 24. JAMA surgery.

Joonas H. Kauppila, MD, Karolinska Institutet, Stockholm, and colleagues evaluated the long-term postoperative course of medications for hyperlipidemia, cardiovascular disease, and diabetes after bariatric surgery. The analysis included 26,396 obese patients who underwent bariatric surgery with gastric bypass or sleeve gastrectomy.

The researchers found that the rate of lipid-lowering drugs after bariatric surgery decreased from 20.3% at baseline to 12.9% at 2 years and 17.6% at 15 years, whereas the no-surgery group used lipid-lowering drugs. have increased from 21.0%. The baseline percent he increased to 44.6 percent after 15 years. There was a decrease in cardiovascular medications (60.2% at baseline and 43.2% at 2 years in bariatric surgery patients) but an increase at 15 years (74.6%). In the non-surgery group, usage increased from 54.4 percent at baseline to 83.3 percent after 15 years. A similar trend was observed for antidiabetic drugs (bariatric surgery group: 27.7% at baseline, 10.0% after 2 years, 23.5% after 15 years, compared to 27.7% at baseline, 54.2% after 15 years).

“Bariatric surgery resulted in significantly longer-lasting reductions in lipid-lowering and antidiabetic drug use compared with no bariatric surgery, whereas cardiovascular drugs , this decline was only temporary,” the authors wrote.

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